Please, check our recent publication in Chemical Biology & Drug Design (IF 4.831), a collaboration with Prof. Lígia Rodrigues lab (Univ. Minho):
Selection of a New peptide homing SK‐BR‐3 breast cancer cells
Ana Cláudia Pereira, Débora Ferreira, Cátia Santos‐Pereira, Tatiana F. Vieira, Sérgio F. Sousa, Goreti Sales, and Lígia R. Rodrigues
DOI: 10.1111/cbdd.13816 | Chemical Biology & Drug Discovery
This paper describes the application of phage display to identify a novel peptide with specificity to the SK‐BR‐3 breast cancer cell line. Cytometry assays confirmed its specificity, while bioinformatics and docking studies predicted the potential biomarkers at the SK‐BR‐3 cells’ surface. These findings can be potentially useful in the clinical context, contributing to more specific and targeted therapeutic solutions against HER2‐positive breast cancer subtypes.
